HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-iodo-1H-imidazole → (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-iodo-1H-imidazole | HCID 2773468 | — |
| Edukt | (S)-5-ethynyl-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 24953136 | — |
| Produkt | (S)-5-(1H-imidazol-2-ylethynyl)-N-[methyl(oxo)phenyl-lambda6-sulfanylidene]nicotinamide | HCID 86629468 | 29% |
Reaktionsschritte
In a manner similar to that describe in Example 434, a mixture of (S)-5-ethynyl-N-[methyl(oxo)phenyl-λ6-sulfanylidene]nicotinamide and 2-iodo-1H-imidazole were reacted to give the title compound as a white solid (15 mg, 29%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07915443B2 |
| Quelldatensatz | uspto-grants-2011_03 |
| ORD ID | ord-0069c148104348e7adccb155949eb00c |
| Quellennotiz | uspto-grants-2011_03 |