Ethanolamine → (S)-N-[{3-[(2-hydroxyethyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Ethanolamine	HCID 700	—
Edukt	N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide	HCID 76585264	—
Produkt	(S)-N-[{3-[(2-hydroxyethyl)amino]propyl}(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide	HCID 57657917	—

Reaktionsschritte

In a manner similar to that described for Example 508, N-[(3-bromopropyl)(oxido)phenyl--sulfanylidene]-5-({3-[(3-methyl-2-furoyl)amino]phenyl}ethynyl)nicotinamide and 2-hydroxyethylamine were converted to the title compound.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07915443B2
Quelldatensatz	uspto-grants-2011_03
ORD ID	ord-44120d62569f4784998dae9e9a6d3fe1
Quellennotiz	uspto-grants-2011_03