Hydrazine → HCID 59216351, Verbindung
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:12]([O:14]C)=O)[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[NH2:16][NH2:17]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2([C:12]([NH:16][NH2:17])=[O:14])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1Komponenten
3
Reaktionsbedingungen
- Temperatur
- 120 °C
Versuchsvorschrift
A mixture of methyl 1-(4-methoxyphenyl)cyclopropanecarboxylate (0.90 g, 4.4 mmol) and hydrazine (0.65 mL, 21 mmol) was heated at 120° C. for 2 h. After cooling, the excess hydrazine was removed under reduced pressure. The residue was treated with water, filtered and washed with water to give the desired product (750 mg, 83%). Analytical LCMS: (M+H)+=207.1.
Aufarbeitung
- temperatureAfter cooling
- customthe excess hydrazine was removed under reduced pressure
- additionThe residue was treated with water
- filtrationfiltered
- washwashed with water
Quellen und Nachweise
- ORD-Eintrag
- ord-aafaf85aaa4a4b608224b07dac8457fa
- Quelldatensatz
- uspto-grants-2011_03
- Patentnummer
- US07915408B2
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