Trifluoroacetic acid → N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

HRID 607614Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 607614
[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH:5]C(=O)OC(C)(C)C.[C:19]([OH:25])([C:21]([F:24])([F:23])[F:22])=[O:20]>C(Cl)Cl>[F:22][C:21]([F:24])([F:23])[C:19]([OH:25])=[O:20].[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH2:5]

Komponenten

4

Edukt 2

HCID 6422Trifluoroacetic acidHCID 59216311Tert-butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate

Produkt 1

HCID 66813129N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

tert-Butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate was stirred with DCM (0.5 ml) and TFA (0.5 ml) for 30 min. The volatiles were removed under reduced pressure to yield the product.

Aufarbeitung

  1. customThe volatiles were removed under reduced pressure
  2. customto yield the product

Quellen und Nachweise

ORD-Eintrag
ord-1c33a2ca1ca6438bb46e2785f4c5d3ff
Quelldatensatz
uspto-grants-2011_03
Patentnummer
US07915408B2

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