HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 607914Erstellt: 25. Oktober 2026
1-Chloro-4-(trifluoromethyl)benzene → 4-Methoxy-4'-trifluoromethyl-biphenyl
https://huagongshe.com/reaction/607914
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | 1-Chloro-4-(trifluoromethyl)benzene | HCID 7394 | — |
| Edukt | (4-Methoxyphenyl)boronic acid | HCID 201262 | — |
| Reagenz | Water | HCID 962 | — |
| Reagenz | Potassium Phosphate, Tribasic | HCID 62657 | — |
| Katalysator | Bis(1,5-cyclooctadiene)nickel | HCID 6433264 | — |
| Katalysator | Bis(3,5-bis(trifluoromethyl)phenyl)(3,6-dimethoxy-2',4',6'-tri(propan-2-yl)(1,1'-biphenyl)-2-yl)phosphane | HCID 44597232 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | 4-Methoxy-4'-trifluoromethyl-biphenyl | HCID 11207478 | 17% |
Reaktionsschritte
pre-ligate Ni(cod)2 and phosphine ligand in dioxane for 15 minutes in a separate plate
Herkunft & Nachweise
| DOI | 10.26434/chemrxiv.14388557.v1 |
|---|
| Quelldatensatz | Ni-catalyzed Suzuki Miyaura cross-coupling |
|---|
| ORD ID | ord-0a99f730b8204d8289f51a940398a1f9 |
|---|
| Quellennotiz | Ni-catalyzed Suzuki Miyaura cross-coupling |
|---|
