HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium Hydroxide → rac-cis-Allyl 2-(((tert-butoxycarbonyl)amino)methyl)-3-methylpiperidine-1-carboxylate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Allyl chloroformate | HCID 18052 | — |
| Edukt | cis-N-Boc-1-(3-methylpiperidin-2-YL)methanamine | HCID 95378400 | — |
| Lösungsmittel | Tetrahydrofuran | HCID 8028 | — |
| Produkt | rac-cis-Allyl 2-(((tert-butoxycarbonyl)amino)methyl)-3-methylpiperidine-1-carboxylate | HCID 131737149 | — |
Reaktionsschritte
To the mixture of rac-cis-tert-butyl ((3-methylpiperidin-2-yl)methyl)carbamate (9.48 g, 41.53 mmol) in THF (25 mL) was added NaOH (2 M, 25 mL), followed by allyl chloroformate (6.65 mL, 62.3 mmol).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09440982B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-b6d9eefc6b694479bdfc197219fb860b |
| Quellennotiz | uspto-grants-2016_09 |