2-Chloro-4-methylpyrimidine → 5-Methyl-2-(4-methyl-2-pyrimidinyl)benzoic acid
Reaktionsgleichung
[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2C=N[CH:14]=[CH:13][N:12]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8].ClC1N=C(C)[CH:21]=[CH:20][N:19]=1>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([C:11]2[N:12]=[C:13]([CH3:14])[CH:21]=[CH:20][N:19]=2)=[C:6]([CH:10]=1)[C:7]([OH:9])=[O:8]Komponenten
3
Versuchsvorschrift
The title compound was prepared following the same general protocol as described for 5-methyl-2-(pyrazin-2-yl)benzoic acid in Example A19, starting from 2-chloro-4-methylpyrimidine. ESI-MS (m/z): 229 [M+1]+.
Quellen und Nachweise
- ORD-Eintrag
- ord-61d3d908da0545979f2fd95da5c839b6
- Quelldatensatz
- uspto-grants-2016_09
- Patentnummer
- US09440982B2
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