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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 61003Erstellt: 24. Oktober 2026

2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane → 3-(4-Fluorophenyl)-6-methylpicolinonitrile

https://huagongshe.com/de/reaction/61003

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-(4-Fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolaneHCID 2760593—
Edukt3-Bromo-6-methylpyridine-2-carbonitrileHCID 21952747—
EduktMethyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoateHCID 117727848—
Produkt3-(4-Fluorophenyl)-6-methylpicolinonitrileHCID 117727830—

Reaktionsschritte

The title compound was synthesized following the same general protocol as described for methyl 5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoate in Example A1, using 2-(4-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane and 3-bromo-6-methylpicolinonitrile. ESI-MS (m/z): 213 [M+1]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09440982B2
Quelldatensatzuspto-grants-2016_09
ORD IDord-86edf712a7304eca955bf69d34893632
Quellennotizuspto-grants-2016_09