Triethylamine → 2-Chloro-n-hydroxy-n-(1-methylethyl)-6-(trimethylsilyl)benzamide

HRID 610925Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 610925
[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[C:4](Cl)=[O:5].Cl.[CH:16]([NH:19][OH:20])([CH3:18])[CH3:17].C(N(CC)CC)C>O1CCOCC1>[Cl:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([Si:11]([CH3:14])([CH3:13])[CH3:12])[C:3]=1[C:4]([N:19]([OH:20])[CH:16]([CH3:18])[CH3:17])=[O:5]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 170873N-Isopropylhydroxylamine HydrochlorideHCID 151835572-Chloro-6-(trimethylsilyl)benzoyl chloride

Produkt 1

HCID 186301502-Chloro-n-hydroxy-n-(1-methylethyl)-6-(trimethylsilyl)benzamide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

The title compound was prepared by reaction of the compound of Example b and the i-propylhydroxylamine hydrochloride in dioxane in the presence of two equivalents of triethylamine using the amination methods described above. m.p. 175-179° C.

Quellen und Nachweise

ORD-Eintrag
ord-f3fa5d39b6fc4c6e9cc5a5477c55ab21
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998466

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