Hydrochloric Acid → 1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-4-phenylbutan-1-one hydrochloride

HRID 611095Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 611095
[CH3:1][N:2]([CH2:4][C:5]1[O:24][C:8]2[CH2:9][N:10]([C:13](=[O:23])[CH2:14][CH2:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:25]>CO.C(OCC)(=O)C>[ClH:25].[CH3:1][N:2]([CH2:4][C:5]1[O:24][C:8]2[CH2:9][N:10]([C:13](=[O:23])[CH2:14][CH2:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 196000511-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-4-phenylbutan-1-one

Produkt 1

HCID 196000501-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-4-phenylbutan-1-one hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-4-phenylbutan-1-one 0.161 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Aufarbeitung

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-3a03cb5889984fa29bde14e97cd765d2
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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