Hydrochloric Acid → N,N-dimethyl-[6-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611105

Reaktionsgleichung

Reaktionsgleichung von HRID 611105
[CH3:1][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:27])[C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:3][N:2]([CH2:4][C:5]1[O:29][C:8]2[CH2:9][N:10]([C:13](=[O:28])[C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:27])[C:21]4[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:1]

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 9800448N,N-Dimethyl-[6-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

Produkt 1

HCID 19600069N,N-dimethyl-[6-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

N,N-Dimethyl-[6-(4-benzoylbenzoyl)-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.329 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was recrystallized from methanol-diethyl ether to yield the desired product.

Aufarbeitung

  1. concentrationAfter this mixture was concentrated
  2. customthe resulting solid was recrystallized from methanol-diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-f36f24b3eb6b471d8bf6e0e2ab98b83a
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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