Hydrochloric Acid → HCID 19600238, Verbindung

HRID 611150Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 611150
[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:28]>CO.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 19600003HCID 19600003, Verbindung

Produkt 1

HCID 19600238HCID 19600238, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-(4-fluorophenyl)hexan-1-one 0.098 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was washed with diethyl ether to yield the desired product.

Aufarbeitung

  1. concentrationAfter this mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-6068050c85114646850f3e70977a81df
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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