Hydrochloric Acid → 1-(2-diethylaminomethyl-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-6-phenylhexan-1-one hydrochloride

HRID 611175

Reaktionsgleichung

Reaktionsgleichung von HRID 611175
[CH2:1]([N:3]([CH2:6][C:7]1[O:15][C:14]2[CH2:13][CH2:12][N:11]([C:16](=[O:28])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:10][C:9]=2[CH:8]=1)[CH2:4][CH3:5])[CH3:2].[ClH:29]>CO>[ClH:29].[CH2:1]([N:3]([CH2:6][C:7]1[O:15][C:14]2[CH2:13][CH2:12][N:11]([C:16](=[O:28])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[CH2:10][C:9]=2[CH:8]=1)[CH2:4][CH3:5])[CH3:2]

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 196001611-(2-diethylaminomethyl-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-6-phenylhexan-1-one

Produkt 1

HCID 196002781-(2-diethylaminomethyl-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-6-phenylhexan-1-one hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

1-(2-Diethylaminomethyl-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl)-6-phenylhexan-1-one 0.209 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

Aufarbeitung

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-25c02bd397284bc1bb5b1ce461bbeba8
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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