HCID 19600120, Verbindung → Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

HRID 611242Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 611242
C([N:8]1[CH2:13][CH2:12][C:11]2[CH:14]=[C:15]([C:17]([O:19][CH3:20])=[O:18])[O:16][C:10]=2[CH2:9]1)C1C=CC=CC=1>CO.[C].[Pd]>[O:16]1[C:10]2[CH2:9][NH:8][CH2:13][CH2:12][C:11]=2[CH:14]=[C:15]1[C:17]([O:19][CH3:20])=[O:18]

Komponenten

4

Edukt 1

HCID 19600120HCID 19600120, Verbindung

Produkt 1

HCID 19600098Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

A solution of 0.285 g (1.050 mmol) of methyl 6-benzyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate in 30 ml of methanol was hydrogenated at room temperature at atmospheric pressure over 0.2 g of 10% palladium-carbon (50% wet) overnight. After the catalyst was filtered off, the filtrate was evaporated under reduced pressure to yield the desired product.

Aufarbeitung

  1. filtrationAfter the catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-bef794c704fe44a4bed37bbfb8a46dbd
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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