Hydrochloric Acid → N,N-dimethyl-[6-[4-(4-methoxybenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611260Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 611260
[CH3:1][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13](=[O:30])[C:14]3[CH:19]=[CH:18][C:17]([C:20](=[O:29])[C:21]4[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=4)=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:32]>CO.C(OCC)(=O)C>[ClH:32].[CH3:1][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13](=[O:30])[C:14]3[CH:15]=[CH:16][C:17]([C:20](=[O:29])[C:21]4[CH:26]=[CH:25][C:24]([O:27][CH3:28])=[CH:23][CH:22]=4)=[CH:18][CH:19]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

Komponenten

5

Edukt 2

HCID 313Hydrochloric AcidHCID 19600048N,N-dimethyl-[6-[4-(4-methoxybenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine

Produkt 1

HCID 19600130N,N-dimethyl-[6-[4-(4-methoxybenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 887MethanolLösungsmittelHCID 8857Ethyl AcetateLösungsmittel

Versuchsvorschrift

N,N-Dimethyl-[6-[4-(4-methoxybenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[2,3-c]pyridin-2-ylmethyl]amine 0.200 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This was concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

Aufarbeitung

  1. concentrationThis was concentrated
  2. washthe resulting solid was washed with diethyl ether

Quellen und Nachweise

ORD-Eintrag
ord-2917a8ae8e8e4fca9efbd863e8b9e3a0
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US05998433

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