HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Isoquinoline-1-carboxylic acid → 2-(((2S,3R)-1-(Isoquinoline-1-carbonyl)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Isoquinoline-1-carboxylic acid | HCID 68092 | — |
| Edukt | 2-(((2S,3R)-3-Methyl-1-(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoyl)piperidin-2-yl)methyl)isoindoline-1,3-dione | HCID 117727726 | — |
| Produkt | 2-(((2S,3R)-1-(Isoquinoline-1-carbonyl)-3-methylpiperidin-2-yl)methyl)isoindoline-1,3-dione | HCID 117727623 | — |
Reaktionsschritte
The title compound was prepared following the same general protocol as described for 2-(((2S,3R)-3-methyl-1-(5-methyl-2-(1-methyl-1H-pyrazol-4-yl)benzoyl)piperidin-2-yl)methyl)isoindoline-1,3-dione in Example A1, using isoquinoline-1-carboxylic acid. ESI-MS (m/z): 414 [M+1]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09440982B2 |
| Quelldatensatz | uspto-grants-2016_09 |
| ORD ID | ord-f3c70c7d7a1046a3843c24188fb49446 |
| Quellennotiz | uspto-grants-2016_09 |