HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
EDTA disodium salt → Diclofenac
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | EDTA disodium salt | HCID 8759 | — |
| Edukt | alpha-Tocopherol succinate | HCID 20353 | — |
| Edukt | Emulphor | HCID 5364713 | — |
| Edukt | 2-[2-(2,6-Dichloroanilino)phenyl]acetic acid;diethylazanium | HCID 86754957 | — |
| Lösungsmittel | Glycerol | HCID 753 | — |
| Produkt | Diclofenac | HCID 3033 | — |
Reaktionsschritte
A diclofenac submicron cream was prepared as follows: Oil phase--diclofenac diethylammonium 12.2 g, MCT oil 170 g, LIPOID E-80 30 g, α-tocopherol succinate 0.4 g; Aqueous phase--EDTA disodium salt 1 g, EMULFOR EL-620 25 g, glycerol 17.5 g, preservatives (methyl and propyl parabens) 0.5 g, reverse osmosis purified water to 1000 g.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06004566 |
| Quelldatensatz | uspto-grants-1999_12 |
| ORD ID | ord-2d9c142721c249ddbbfea422e455589d |
| Quellennotiz | uspto-grants-1999_12 |