4-Fluoro-3-methoxymethoxy-5-phenylisoxazole → HCID 178519001, Verbindung

HRID 612924Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 612924
[F:1][C:2]1[C:3]([O:13]COC)=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>Cl.O1CCOCC1>[F:1][C:2]1[C:3]([OH:13])=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

Komponenten

3

Edukt 1

HCID 195967054-Fluoro-3-methoxymethoxy-5-phenylisoxazole

Produkt 1

HCID 178519001HCID 178519001, VerbindungAusbeute 84,9 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 204431481,4-Dioxane hydrochlorideLösungsmittel

Versuchsvorschrift

4-Fluoro-3-methoxymethoxy-5-phenylisoxazole (0.44 g) was dissolved in a solution of 4N hydrochloric acid/dioxane (5.0 ml), and the solution was stirred at room temperature for one hour. After the reaction, the solvent was evaporated under reduced pressure and the crystal thus obtained was washed with dichloromethane (10 ml) to obtain the title compound (0.30 g, 83%) as colorless crystals.

Aufarbeitung

  1. customAfter the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. customthe crystal thus obtained
  4. washwas washed with dichloromethane (10 ml)

Quellen und Nachweise

ORD-Eintrag
ord-3a43b3fe7e1247b4bd4d2510ffd293a6
Quelldatensatz
uspto-grants-1999_12
Patentnummer
US06005116

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