Dimethylformamide → HCID 20563052, Verbindung

HRID 613982

Reaktionsgleichung

Reaktionsgleichung von HRID 613982
N[C:2]1[O:3][C:4]2[CH:14]=[CH:13][CH:12]=[CH:11][C:5]=2[C:6](=[O:10])[C:7]=1C=O.[C:15]([C:17]#[CH:18])#[N:16].[CH3:19][N:20](C)C=O>>[C:15]([C:17]1[CH:19]=[N:20][C:7]2[C:6](=[O:10])[C:5]3[C:4]([O:3][C:2]=2[CH:18]=1)=[CH:14][CH:13]=[CH:12][CH:11]=3)#[N:16]

Komponenten

4

Edukt 3

HCID 6228DimethylformamideHCID 140552-PropynenitrileHCID 7359282-Aminochromone-3-carboxaldehyde

Produkt 1

HCID 20563052HCID 20563052, Verbindung

Reaktionsbedingungen

Temperatur
140 °C

Versuchsvorschrift

To 70 ml of dimethylformamide was added 2.2 g of 2-amino-4-oxo-4H-1-benzopyran-3-carboxaldehyde, followed by the addition of 2.5 g of cyanoacetylene. The mixture was heated under stirring at 140° C. for 15 hours and the solvent was then distilled off under reduced pressure. The residue was chromatographed on silica gel and eluted with chloroform and recrystallized from acetonitrile to give 0.83 g of 3-cyano-1-azaxanthone as crystals, m.p. 220°-226° C.

Aufarbeitung

  1. temperatureThe mixture was heated
  2. distillationthe solvent was then distilled off under reduced pressure
  3. customThe residue was chromatographed on silica gel
  4. washeluted with chloroform
  5. customrecrystallized from acetonitrile

Quellen und Nachweise

ORD-Eintrag
ord-53216e11e18842ada0acdfc09a4e3e2b
Quelldatensatz
uspto-grants-1979_03
Patentnummer
US04143042

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