Nitric Acid → 3-Bromo-2-nitro-1-benzofuran

HRID 614358

Reaktionsgleichung

Reaktionsgleichung von HRID 614358
[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][CH:3]=1.[N+:11]([O-])([OH:13])=[O:12].N([O-])=O.[Na+]>CO>[Br:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]=1[N+:11]([O-:13])=[O:12]

Komponenten

5

Edukt 3

HCID 944Nitric Acid2×HCID 6405893-Bromo-1-benzofuranHCID 23668193Sodium Nitrite

Produkt 1

HCID 135098423-Bromo-2-nitro-1-benzofuran

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

A 5.0 g. sample of powdered 3-bromobenzofuran on a glass dish is placed next to a container of nitric acid. Sodium nitrite is added periodically to the nitric acid, and the entire experiment is covered with a bell jar. After about 15 minutes the powder becomes an oil. After 12 hours the product is dissolved in hot methanol and slowly crystallized by cooling. Recrystallization from methanol provides yellow crystals of 3-bromo-2-nitrobenzofuran, m.p. 130°-132° C. (lit. 132° C.).

Aufarbeitung

  1. customslowly crystallized
  2. temperatureby cooling
  3. customRecrystallization from methanol

Quellen und Nachweise

ORD-Eintrag
ord-e8b879d8638c47dbba8295506a30c2d9
Quelldatensatz
uspto-grants-1979_03
Patentnummer
US04144347

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