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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 614473Erstellt: 25. Oktober 2026

1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl ester → cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamide

https://huagongshe.com/reaction/614473

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-Pyrrolidineacetic acid, 2-methyl-5-oxo-, ethyl esterHCID 574476—
Edukt2-(cis-2,6-Dimethyl-1-piperidinyl)ethanamineHCID 783702—
Produktcis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamideHCID 70610011—

Reaktionsschritte

From 9.26 g. of ethyl 2-methyl-5-oxo-1-pyrrolidineacetate (British Pat. No. 1,309,692) and 8.6 g. of cis-2-(2,6-dimethyl-1-piperidinyl)ethylamine, following the procedure of Example 9, there is obtained cis-N-[2-(2,6-dimethyl-1-piperidinyl)ethyl]-2-methyl-5-oxo-1-pyrrolidineacetamide; m.p. 115°-116° C. after crystallization from cyclohexane.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS04145347
Quelldatensatzuspto-grants-1979_03
ORD IDord-88dc0e06b5634809b2f665ef092cad30
Quellennotizuspto-grants-1979_03