cis-3-[2,6-Dimethylpiperidinyl]propylamine → cis-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-2,2-dimethyl-5-oxo-1-pyrrolidineacetamide
Reaktionsgleichung
[CH3:1][C:2]1([CH3:14])[CH2:6][CH2:5][C:4](=[O:7])[N:3]1[CH2:8][C:9]([O:11]CC)=O.[CH3:15][C@H:16]1[CH2:21][CH2:20][CH2:19][C@@H:18]([CH3:22])[N:17]1[CH2:23][CH2:24][CH2:25][NH2:26]>>[CH3:15][C@H:16]1[CH2:21][CH2:20][CH2:19][C@@H:18]([CH3:22])[N:17]1[CH2:23][CH2:24][CH2:25][NH:26][C:9](=[O:11])[CH2:8][N:3]1[C:4](=[O:7])[CH2:5][CH2:6][C:2]1([CH3:1])[CH3:14]Komponenten
3
Versuchsvorschrift
From 10 g. of ethyl 2,2-dimethyl-5-oxopyrrolidineacetate, (British Pat. No. 1,309,692) and 10.5 g. of cis-3-(2,6-dimethyl-1-piperidinyl)propylamine, following the procedure of Example 9, there is obtained cis-N-[3-(2,6-dimethyl-1-piperidinyl)propyl]-2,2-dimethyl-5-oxo-1-pyrrolidineacetamide; m.p. 86°-87° C. after crystallization from isooctane.
Quellen und Nachweise
- ORD-Eintrag
- ord-ea65949aeb2a4b9e9902112d0ba12b29
- Quelldatensatz