Hydrochloric Acid → 2-Acetoxyethyl chloromethyl sulfide
Reaktionsgleichung
[ClH:1].[C:2]([O:5][CH2:6][CH2:7][SH:8])(=[O:4])[CH3:3].[CH2:9]=O.[Cl-].[Ca+2].[Cl-]>C(Cl)Cl>[Cl:1][CH2:9][S:8][CH2:7][CH2:6][O:5][C:2](=[O:4])[CH3:3]Komponenten
6
Edukt 4
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Hydrogen chloride gas was introduced into a mixture of 2-acetoxyethanethiol (24.0 g) and paraformaldehyde (6.0 g) at a moderate rate with external cooling for 3 hours. Calcium chloride (25 g) was added and the reaction mixture allowed to stand in a salt-ice bath for 4 hours. Methylene chloride (200 ml) was added, the reaction mixture filtered and the solvent evaporated with rigorous exclusion of moisture. The residual oil was distilled to give 2-acetyloxyethyl chloromethyl sulfide (18.5 g, bp 82°-87° C. at 3 mm Hg).
Aufarbeitung
- temperaturewith external cooling for 3 hours
- filtrationthe reaction mixture filtered
- customthe solvent evaporated with rigorous exclusion of moisture
- distillationThe residual oil was distilled
Quellen und Nachweise
- ORD-Eintrag
- ord-52af1e3fbe744eaab20084b38289c475
- Quelldatensatz
- uspto-grants-1979_03
- Patentnummer
- US04146715
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