Methoxycarbonyl isothiocyanate → 4-Carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene
Reaktionsgleichung
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9](=[O:11])[NH2:10])=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[CH3:15][O:16][C:17]([N:19]=[C:20]=[S:21])=[O:18]>CC(C)=O>[C:9]([S:8][C:5]1[CH:6]=[CH:7][C:2]([NH:1][C:20]([NH:19][C:17]([O:16][CH3:15])=[O:18])=[S:21])=[C:3]([N+:12]([O-:14])=[O:13])[CH:4]=1)(=[O:11])[NH2:10]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
1 G. of 1-amino-4-carbamoylthio-2-nitrobenzene in 20 ml. acetone is treated with 3.0 g. methoxy carbonyl isothiocyanate at room temperature for several days. The solution is concentrated and the residue triturated with methanol to afford 4-carbamoylthio-1-(3-methoxycarbonyl-2-thioureido)-2-nitrobenzene.