beta-Aminobeta-ethoxyacrylic acid ethyl ester → 3-Amino-1-(4-bromobenzyl)-pyrazol-5one

HRID 617017Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 617017
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.[Br:12][C:13]1[CH:21]=[CH:20][C:16]([CH2:17][NH:18][NH2:19])=[CH:15][CH:14]=1>>[NH2:10][C:6]1[NH:19][N:18]([CH2:17][C:16]2[CH:20]=[CH:21][C:13]([Br:12])=[CH:14][CH:15]=2)[C:4](=[O:3])[CH:5]=1

Komponenten

3

Edukt 2

HCID 278451beta-Aminobeta-ethoxyacrylic acid ethyl esterHCID 167731114-Bromobenzylhydrazine

Produkt 1

HCID 203672113-Amino-1-(4-bromobenzyl)-pyrazol-5one

Versuchsvorschrift

17.5 g of β-amino-β-ethoxyacrylic acid ethyl ester and 20 g of 4-bromobenzylhydrazine, on stirring for 5 hours in alcohol at 50° and working up as described in Example 1, yield 15.6 g of the compound identified above, corresponding to 58% of theory, as colorless crystals of melting point 139°.

Quellen und Nachweise

ORD-Eintrag
ord-286fde6be7174b9ba3c1e9381e986901
Quelldatensatz
uspto-grants-1978_02
Patentnummer
US04076943

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