Diethyl ethylmalonate → 2-Amino-2-ethyl-4-(4-octylphenyl)butanol

HRID 617600Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 617600
C([O:4][CH2:5][C:6]([NH:26]C(=O)C)([CH2:24][CH3:25])[CH2:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15](=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:11][CH:10]=1)(=O)C.C(OC(=O)C(CC)C(OCC)=O)C>>[NH2:26][C:6]([CH2:24][CH3:25])([CH2:7][CH2:8][C:9]1[CH:10]=[CH:11][C:12]([CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22])=[CH:13][CH:14]=1)[CH2:5][OH:4]

Komponenten

3

Edukt 2

HCID 8610Diethyl ethylmalonateHCID 53718772HCID 53718772, Verbindung

Produkt 1

HCID 226187412-Amino-2-ethyl-4-(4-octylphenyl)butanol

Versuchsvorschrift

In working example 77, 2-acetamido-2-ethyl-4-(4-octanoylphenyl)butyl acetate obtained by using ethylmalonic acid diethyl ester instead of propylmalonic acid diethyl ester, is subjected to reduction in the same manner as working example 2 (7) and then hydrolysis in the same manner as working example 78 to give the subject compound.

Aufarbeitung

  1. customobtained
  2. customhydrolysis in the same manner
  3. customto give the subject compound

Quellen und Nachweise

ORD-Eintrag
ord-987750befa8a4f81a0b4da325a5bdbb5
Quelldatensatz
uspto-grants-1999_09
Patentnummer
US05948820

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