HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Benzyloxycarbonylamino3-([1,8]naphthyridin-2-yl)-propane → 3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Benzyloxycarbonylamino3-([1,8]naphthyridin-2-yl)-propane | HCID 21850009 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | HCID 178418390 | HCID 178418390 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Produkt | 3-(5,6,7,8-Tetrahydro-1,8-naphthyridin-2-yl)propan-1-amine | HCID 9877599 | — |
Reaktionsschritte
A mixture of 1-7 (0.40 g, 1.24 mmol) and 10% Pd/carbon (0.08 g) in EtOH (12 mL) was stirred under a balloon of hydrogen for 20 h. Filtration through a celite pad and then evaporative removal of the filtrate solvent gave 1-8 as a colorless oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05952341 |
| Quelldatensatz | uspto-grants-1999_09 |
| ORD ID | ord-b76cde09736546e88cde543518f2299b |
| Quellennotiz | uspto-grants-1999_09 |