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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 618114Erstellt: 25. Oktober 2026

3',4',5'-Trimethoxyacetophenone → (E)-3-(6-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-one

https://huagongshe.com/reaction/618114

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt3',4',5'-TrimethoxyacetophenoneHCID 14345—
Edukt6-Methoxy-1H-indole-3-carboxaldehydeHCID 907214—
Produkt(E)-3-(6-Methoxyindol-3-yl)-1-(3,4,5-trimethoxyphenyl)-2-propen-1-oneHCID 2185028332%

Reaktionsschritte

Substantially the same procedure as in Example 1 was repeated using 3',4',5'-trimethoxyacetophenone (659 mg) and 6-methoxyindole-3-carboxaldehyde (550 mg) except that the reaction solution was concentrated under reduced pressure, that the residue was purified by silica gel column chromatography, and that the obtained crude crystals were recrystallized from ethanol, to give Compound 39 (369 mg).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05952355
Quelldatensatzuspto-grants-1999_09
ORD IDord-f3c262c37ecd43e0955d3e99bad2ecf7
Quellennotizuspto-grants-1999_09