HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Toluene → 2-Diethylphosphinoylmethyl-1,3-dioxolane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Toluene | HCID 1140 | — |
| Edukt | 3-Bromo-1,2-propanediol | HCID 20827 | — |
| Edukt | Diethyl (2,2-diethoxyethyl)phosphonate | HCID 82071 | — |
| Katalysator | p-Toluenesulfonic acid | HCID 6101 | — |
| Produkt | 2-Diethylphosphinoylmethyl-1,3-dioxolane | HCID 21255858 | — |
Reaktionsschritte
Diethylphosphonoacetaldehyde diethylacetal (VIIa) was condensed with 3-bromo-1,2-propanediol (Va) in the presence of p-toluenesulfonic acid as a catalyst and reflux in toluene to yield 2-diethylphosphinoylmethyl-1,3-dioxolane of formula (IId) as a mixture of cis and trans isomers;
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05955610 |
| Quelldatensatz | uspto-grants-1999_09 |
| ORD ID | ord-28f763d1a48a439da5d13db97540678e |
| Quellennotiz | uspto-grants-1999_09 |