2-Tert-butylpropanedioic acid → 4-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

HRID 61895Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 61895
[CH3:1][O:2][C:3]1[N:8]=[C:7]([C:9]([CH3:14])([CH3:13])[C:10]([OH:12])=O)[CH:6]=[CH:5][CH:4]=1.C([CH:19]([C:23]([OH:25])=[O:24])C(O)=O)(C)(C)C>>[C:9]([O:25][C:23](=[O:24])[CH2:19][C:10](=[O:12])[C:9]([C:7]1[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=1)([CH3:14])[CH3:13])([CH3:13])([CH3:10])[CH3:7]

Komponenten

3

Edukt 2

HCID 2427522-Tert-butylpropanedioic acidHCID 668349942-(6-Methoxypyridin-2-yl)-2-methylpropanoic acid

Produkt 1

HCID 668345394-(6-Methoxy-pyridin-2-yl)-4-methyl-3-oxo-pentanoic acid tert-butyl ester

Versuchsvorschrift

The title compound was synthesized from 2-(6-methoxy-pyridin-2-yl)-2-methyl-propionic acid and mono-tert-butyl malonic acid according to the method used for the synthesis of Compound PR4. The resultant was used for the next step without further purification.

Aufarbeitung

  1. customused for the synthesis of Compound PR4
  2. customThe resultant was used for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-60e0ae8c3d4c4b138837dde5fb727092
Quelldatensatz
uspto-grants-2016_09
Patentnummer
US09440922B2

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