Ammonia → HCID 21248422, Verbindung

Reaktionsgleichung

[NH2:1][C:2]1[CH:10]=[C:9]([CH3:11])[CH:8]=[CH:7][C:3]=1[NH:4][CH2:5][CH3:6].Cl.[Cl:13][CH2:14][C:15](O)=O.N>>[CH2:5]([N:4]1[C:3]2[CH:7]=[CH:8][C:9]([CH3:11])=[CH:10][C:2]=2[N:1]=[C:15]1[CH2:14][Cl:13])[CH3:6]

Komponenten

Edukt 4

HCID 222Ammonia

HCID 300Chloroacetic Acid

HCID 313Hydrochloric Acid

HCID 14243606N1-ethyl-4-methylbenzene-1,2-diamine

Produkt 1

HCID 21248422HCID 21248422, VerbindungAusbeute 27,9 %

Versuchsvorschrift

2-amino-4-methyl-N-ethylaniline (2.15 g, 14 mmol), which is a known compound, hydrochloric acid (4N, 15 ml) and monochloroacetic acid (2 g, 21 mmol) were refluxed for 2.5 hours. After cooling, the reactant was neutralized with ammonia. The occurred oily substance was extracted with ethyl acetate and the product was treated as in a usual process to obtain the title intermediate (1.0 g, 3.9 mmol).