Acetyl chloride → N-[2-(Acetyloxy)ethyl]-N,N-dimethyldodecan-1-aminium bromide

HRID 621607Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 621607
[Br-:1].[CH2:2]([N+:14]([CH3:19])([CH3:18])[CH2:15][CH2:16][OH:17])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].C(=O)([O-])[O-].[Na+].[Na+].[C:26](Cl)(=[O:28])[CH3:27]>CC(C)=O>[Br-:1].[CH2:2]([N+:14]([CH3:19])([CH3:18])[CH2:15][CH2:16][O:17][C:26](=[O:28])[CH3:27])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13]

Komponenten

5

Edukt 3

HCID 6367Acetyl chlorideHCID 10340Sodium CarbonateHCID 814861-Dodecanaminium, N-(2-hydroxyethyl)-N,N-dimethyl-, bromide (1:1)

Produkt 1

HCID 13914766N-[2-(Acetyloxy)ethyl]-N,N-dimethyldodecan-1-aminium bromide

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Reaktionsbedingungen

Temperatur
60 °C

Versuchsvorschrift

In a reaction vessel was placed 13.14 grams of dodecyl dimethyl 2-hydroxyethyl ammonium bromide, 21.22 grams of acetone solvent and 4.72 grams of sodium carbonate. While stirring under nitrogen, 3.27 grams of acetyl chloride was added dropwise. Gas evolution occurred. The mixture was then refluxed (approx. 60° C.) for 6 hours. The solvent was removed under vacuum. The residue was extracted with isopropanol to dissolve the quat and the solution was filtered hot to removed sodium chloride and sodium carbonate. The filtrate was evaporated under vacuum leaving as the product dodecyl dimethyl acetyloxyethyl ammonium bromide.

Aufarbeitung

  1. customIn a reaction vessel was placed
  2. customThe solvent was removed under vacuum
  3. extractionThe residue was extracted with isopropanol
  4. dissolutionto dissolve the quat
  5. filtrationthe solution was filtered hot
  6. customto removed sodium chloride and sodium carbonate
  7. customThe filtrate was evaporated under vacuum

Quellen und Nachweise

ORD-Eintrag
ord-ad80dc4138404862b21d909f7f27b461
Quelldatensatz
uspto-grants-1989_04
Patentnummer
US04824867

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