Dimethyl Sulfate → Methyl 3-methoxy-4-phenylthiobenzoate

HRID 621632Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 621632
[OH:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:5]([O:7][CH3:8])=[S:6].[C:18](=O)([O-])[O-].[K+].[K+].S(OC)(OC)(=O)=O>CC(C)=O>[CH3:18][O:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[C:5]([O:7][CH3:8])=[S:6]

Komponenten

5

Edukt 3

HCID 6497Dimethyl SulfateHCID 11430Potassium CarbonateHCID 54152449Methyl 3-hydroxy-4-phenylthiobenzoate

Produkt 1

HCID 53705693Methyl 3-methoxy-4-phenylthiobenzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a mixture of methyl 3-hyroxy-4-phenylthiobenzoate (49.11 g), potassium carbonate (27.33 g) and acetone (627 ml) is added dimethyl sulfate (17.85 ml), and the mixture is refluxed with stirring for 6 hours. The reaction mixture is cooled, and the precipitate is separated by filtration and washed with acetone. The filtrate and washings are combined and concentrated under reduced pressure to give methyl 3-methoxy-4-phenylthiobenzoate.

Aufarbeitung

  1. temperaturethe mixture is refluxed
  2. temperatureThe reaction mixture is cooled
  3. customthe precipitate is separated by filtration
  4. washwashed with acetone
  5. concentrationconcentrated under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-8440b4cb552d42218a6e6e287f51bd36
Quelldatensatz
uspto-grants-1989_04
Patentnummer
US04824834

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