Ethanol → HCID 21294041, Verbindung

HRID 622245Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 622245
[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2].S(=O)(=O)(O)O.[CH2:27](O)[CH3:28]>>[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH2:27][CH3:28])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2]

Komponenten

4

Edukt 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 13753872HCID 13753872, Verbindung

Produkt 1

HCID 21294041HCID 21294041, Verbindung

Versuchsvorschrift

Eleven grams of 5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentanoic acid were dissolved in 200 ml. of absolute ethanol. With stirring, 1 ml. of sulfuric acid was added and the reaction was stirred overnight. The solvent was evaporated in vacuo and the residue partitioned between ethyl acetate and dilute potassium carbonate solution. The ethyl acetate was separated, dried, and evaporated to give 9.9 g. of the title product, M+ =322.

Aufarbeitung

  1. stirringthe reaction was stirred overnight
  2. customThe solvent was evaporated in vacuo
  3. customthe residue partitioned between ethyl acetate and dilute potassium carbonate solution
  4. customThe ethyl acetate was separated
  5. customdried
  6. customevaporated
  7. customto give 9.9 g

Quellen und Nachweise

ORD-Eintrag
ord-dd06da591652446e9be57de52ed9e061
Quelldatensatz
uspto-grants-1988_09
Patentnummer
US04769482

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