Methyl iodide → HCID 88521502, Verbindung

HRID 622315

Reaktionsgleichung

Reaktionsgleichung von HRID 622315
[CH3:1][CH2:2][O:3][C:4]([C:6]1[N:10]([CH:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH3:12])[CH:9]=[N:8][CH:7]=1)=[O:5].[I:19][CH3:20]>ClCCl>[I-:19].[CH2:2]([O:3][C:4]([C:6]1[NH+:10]([CH:11]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH3:12])[CH2:9][N:8]([CH3:20])[CH:7]=1)=[O:5])[CH3:1]

Komponenten

4

Edukt 2

HCID 6328Methyl iodideHCID 36339Ethnor

Produkt 1

HCID 88521502HCID 88521502, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

To a stirred solution of 7 parts of R-(+) ethyl 1-(1-phenylethyl)-1H-imidazole-5-carboxylate in 19.5 parts of iodomethane were added 21.3 parts of dichloromethane and the whole was stirred for 24 hours at room temperature. The reaction mixture was evaporated and the residue was crystallized from 2-propanol. The product was filtered off and washed with petroleum ether, yielding 7.03 parts of 5-ethoxycarbonyl-3-methyl-1-(1-phenylethyl)-1H-imidazolium iodide; mp. 159.5° C.; [α]D =-62.79° (10% water).

Aufarbeitung

  1. customThe reaction mixture was evaporated
  2. customthe residue was crystallized from 2-propanol
  3. filtrationThe product was filtered off
  4. washwashed with petroleum ether

Quellen und Nachweise

ORD-Eintrag
ord-47aabe38e2c64e22973abf66b181e665
Quelldatensatz
uspto-grants-1988_09
Patentnummer
US04770689

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