Dimethyl acetylenedicarboxylate → 1-(3-Methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dimethyl acetylenedicarboxylate	HCID 12980	—
Edukt	4-Ethoxy-3-methoxybenzaldehyde	HCID 67116	—
Edukt	2-Bromo-3,4,5-trimethoxybenzaldehyde dimethylacetal	HCID 15914458	—
Produkt	1-(3-Methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene	HCID 13910827	67%

Reaktionsschritte

2-Bromo-3,4,5-trimethoxybenzaldehyde dimethylacetal, 3-methoxy-4-ethoxybenzaldehyde and dimethyl acetylenedicarboxylate are treated in the same manner as described in Example 1, whereby 1-(3-methoxy-4-ethoxyphenyl)-2,3-bis(methoxycarbonyl)-4-hydroxy-6,7,8-trimethoxynaphthalene is obtained as colorless needles. Yield: 67%

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US04771072
Quelldatensatz	uspto-grants-1988_09
ORD ID	ord-68abce3b5cf34756a1620115ccb7ff85
Quellennotiz	uspto-grants-1988_09