HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Methylmethanesulfonamide → 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N-Methylmethanesulfonamide | HCID 97632 | — |
| Edukt | Methyl 4-fluoro-2-(methylamino)benzoate | HCID 13474393 | — |
| Edukt | Butyllithium | HCID 178418339 | — |
| Produkt | 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone | HCID 21291484 | — |
Reaktionsschritte
In a similar manner to that described in Example 12(a), N-methylmethanesulphonamide was reacted with n-butyl lithium and the product reacted with methyl 4-fluoro-2-methylaminobenzoate to give the novel compound 1-(4-fluoro-2-methylaminophenyl)-2-(N-methylsulphamoyl)ethanone, m.p. 140°-142°.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04772614 |
| Quelldatensatz | uspto-grants-1988_09 |
| ORD ID | ord-63e621efc46e492b838d0e66c85af94a |
| Quellennotiz | uspto-grants-1988_09 |