HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrahydrofurfuryl alcohol → 6-((Tetrahydrofuran-2-yl)methoxy)-5-(trifluoromethyl)picolinic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrahydrofurfuryl alcohol | HCID 7360 | — |
| Edukt | Potassium Hydroxide | HCID 14797 | — |
| Edukt | 6-Chloro-5-(trifluoromethyl)picolinic acid | HCID 70701016 | — |
| Produkt | 6-((Tetrahydrofuran-2-yl)methoxy)-5-(trifluoromethyl)picolinic acid | HCID 71087646 | — |
Reaktionsschritte
In analogy to the procedure described in Example 4 a), 6-chloro-5-(trifluoromethyl)picolinic acid (CAN 855915-21-8) was reacted with (tetrahydrofuran-2-yl)methanol (CAN 97-99-4) in the presence of potassium hydroxide to yield the title compound as yellow solid; MS (EI): m/e=290.0 [MH+].
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09303012B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-36267bffa0e54c9aab12d608f074bb6f |
| Quellennotiz | uspto-grants-2016_04 |