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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 626059Erstellt: 26. Oktober 2026

1-(3,4-Difluorophenyl)ethan-1-one → 1-{4-[2-(Benzyloxy)-4-ethylphenoxy]-3-fluorophenyl}ethanone

https://huagongshe.com/reaction/626059

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(3,4-Difluorophenyl)ethan-1-oneHCID 123052—
Edukt3-Fluoro-2-nitropyridineHCID 2762802—
Edukt2-(Benzyloxy)-4-ethylphenolHCID 59191243—
Produkt1-{4-[2-(Benzyloxy)-4-ethylphenoxy]-3-fluorophenyl}ethanoneHCID 5919140196%

Reaktionsschritte

According to the procedure of example 21 (a3) except substituting 4-Ethyl-2-methoxy phenol by 2-(benzyloxy)-4-ethylphenol (1.3 g, 5.7 mmol) and 3-Fluoro-2-nitropyridine by 1-(3,4-difluorophenyl)ethanone (0.98 g, 6.27 mmol), the title compound was prepared as a clear oil in 96% yield (2 g) and used without further purification.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09309179B2
Quelldatensatzuspto-grants-2016_04
ORD IDord-5af2dfcfa98c421bb2f57be5933723f6
Quellennotizuspto-grants-2016_04