alpha-Methyl-4-(2-methylpropyl)benzeneacetyl chloride → 3-Acetamidobicyclo[1.1.1]pentan-1-yl 2-(4-isobutylphenyl)propanoate

HRID 62622

Reaktionsgleichung

Reaktionsgleichung von HRID 62622
[OH:1][C:2]12[CH2:6][C:4]([NH:7][C:8](=[O:10])[CH3:9])([CH2:5]1)[CH2:3]2.[CH2:11]([C:15]1[CH:20]=[CH:19][C:18]([CH:21]([CH3:25])[C:22](Cl)=[O:23])=[CH:17][CH:16]=1)[CH:12]([CH3:14])[CH3:13]>>[CH2:11]([C:15]1[CH:16]=[CH:17][C:18]([CH:21]([CH3:25])[C:22]([O:1][C:2]23[CH2:6][C:4]([NH:7][C:8](=[O:10])[CH3:9])([CH2:5]2)[CH2:3]3)=[O:23])=[CH:19][CH:20]=1)[CH:12]([CH3:14])[CH3:13]

Komponenten

3

Edukt 2

HCID 595157alpha-Methyl-4-(2-methylpropyl)benzeneacetyl chlorideHCID 86287953N-{3-hydroxybicyclo[1.1.1]pentan-1-yl}acetamide

Produkt 1

HCID 862880283-Acetamidobicyclo[1.1.1]pentan-1-yl 2-(4-isobutylphenyl)propanoate

Versuchsvorschrift

The general procedure of Example 1 Step 3 is repeated starting with N-(3-hydroxybicyclo[1.1.1]pentan-1-yl)acetamide (1) and using 2-(4-isobutylphenyl)propanoyl chloride in place of the acetyl chloride to produce compound 9.

Quellen und Nachweise

ORD-Eintrag
ord-8bbe225f27ca4062ab6ca60f23cbc351
Quelldatensatz
uspto-grants-2016_09
Patentnummer
US09447026B2

Verknüpfte Notizen

Wird geladen…