Hydrochloric Acid → 1-(4-Bromophenyl)ethylamine hydrochloride

HRID 626400Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 626400
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]([NH:10][S@](C(C)(C)C)=O)[CH3:9])=[CH:4][CH:3]=1.[ClH:17]>CO>[ClH:17].[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]([NH2:10])[CH3:9])=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 313Hydrochloric AcidHCID 86732639HCID 86732639, Verbindung

Produkt 1

HCID 534848701-(4-Bromophenyl)ethylamine hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

(S)—N—((S)-1-(4-bromophenyl)ethyl)-2-methylpropane-2-sulfinamide (170 mg, 0.56 mmol) was dissolved in methanol (2 mL) followed by addition of con.HCl (1 mL). The mixture was stirred at RT for 4 h and then was concentrated and evaporated with toluene twice to afford the titled compound.

Aufarbeitung

  1. additionfollowed by addition of con
  2. concentrationwas concentrated
  3. customevaporated with toluene twice

Quellen und Nachweise

ORD-Eintrag
ord-2c4a12918ec54afba31feacce594bbd3
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09309227B2

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