(E)-3-(4-benzyloxy-3-fluoro-phenyl)-acrylic acid methyl ester → HCID 22558806, Verbindung

Beteiligte Stoffe

Reaktionsschritte

(E)-3-(4-Benzyloxy-3-fluoro-phenyl)-acrylic acid methyl ester (0.37 g, 1.2 mmol) obtained in Step B was dissolved in EtOAc (4 mL) and MeOH (2 mL). The solution was added with 10% Pd/C (0.03 g), and the mixture was stirred under hydrogen atmosphere for 18 hours. The reactant was filtered by using celite, and the filtrate was washed with EtOAc to obtain the title compound (0.25 g, 98%).

Herkunft & Nachweise