Bromocyclopentane → 2-(Cyclopentylsulfanyl)pyridine-3-carboxylic acid
Reaktionsgleichung
[SH:1][C:2]1[N:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Br[CH:12]1[CH2:16][CH2:15][CH2:14][CH2:13]1>>[CH:12]1([S:1][C:2]2[N:10]=[CH:9][CH:8]=[CH:7][C:3]=2[C:4]([OH:6])=[O:5])[CH2:16][CH2:15][CH2:14][CH2:13]1Komponenten
3
Versuchsvorschrift
2-Mercapto-nicotinic acid (1.0 g, 6.44 mmol) and bromo-cyclopentane (2 mL, 19.33 mmol) were reacted in the same manner as in Step A of Preparation Example 1 to obtain the title compound, which was used in the next step without a separate purification process.
Quellen und Nachweise
- ORD-Eintrag
- ord-3a309bac34724c338a028dcc1296b76d
- Quelldatensatz
- uspto-grants-2016_09
- Patentnummer
- US09447044B2
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