Isopropyl iodide → 3-Isopropylsulfanyl-pyrazine-2-carboxylic acid methyl ester
Reaktionsgleichung
[CH3:1][O:2][C:3]([C:5]1[C:10]([SH:11])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].I[CH:13]([CH3:15])[CH3:14]>>[CH3:1][O:2][C:3]([C:5]1[C:10]([S:11][CH:13]([CH3:15])[CH3:14])=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4]Komponenten
3
Versuchsvorschrift
3-Mercapto-pyrazine-2-carboxylic acid methyl ester (0.35 g, 2.0 mmol) obtained in Step A and 2-iodopropane were reacted in the same manner as in Step A of Preparation Example 5 to obtain the title compound (0.267 g, 61%).
Quellen und Nachweise
- ORD-Eintrag
- ord-9c6637ca917049fabc1a23509cbfe685
- Quelldatensatz
- uspto-grants-2016_09
- Patentnummer
- US09447044B2
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