HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Toluenesulfonyl chloride → 3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-Toluenesulfonyl chloride | HCID 7397 | — |
| Edukt | 3-(4-Hydroxybutyl)-1H-indole-5-carbonitrile | HCID 12150985 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | 3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile | HCID 56952267 | — |
Reaktionsschritte
3-[4-(p-Toluenesulfonyloxy)butyl]-1H-indole-5-carbonitrile was prepared by reacting 3-(4-hydroxybutyl)-1H-indole-5-carbonitrile with p-toluenesulfonyl chloride in the presence of base in dichloromethane as per the process exemplified in example 2 of Chinese Patent Application Publication No. CN 102267932 A.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09315456B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-de1fb67b6cc7491288925f091e7cefa9 |
| Quellennotiz | uspto-grants-2016_04 |