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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 62925Erstellt: 25. Oktober 2026

Ethyl 3-(3,5-difluoro-4-hydroxyphenyl)propanoate → HCID 74222281, Verbindung

https://huagongshe.com/reaction/62925

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEthyl 3-(3,5-difluoro-4-hydroxyphenyl)propanoateHCID 23136305—
Edukt2-Butylsulfanyl-3-chloromethyl-pyridineHCID 90118254—
ProduktHCID 74222281HCID 7422228176%

Reaktionsschritte

3-Chloromethyl-2-ethylsulfanyl-pyridine (0.1 g, 0.53 mmol) obtained in Step C of Preparation Example 11 and 3-(3,5-difluoro-4-hydroxy-phenyl)-propionic acid ethyl ester (0.12 g, 0.53 mmol) obtained in Step D of Preparation Example 2 were used to react sequentially in the same manner as in Steps A and B of Example 1 to obtain the title compound (76% yield).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09447044B2
Quelldatensatzuspto-grants-2016_09
ORD IDord-d8ceb9879ce342de806ce711e0c7be7b
Quellennotizuspto-grants-2016_09