2-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amine → 5-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

HRID 632053Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 632053
[CH:1]1([C:6]2[CH:7]=[CH:8][C:9]([C:17]([OH:19])=O)=[N:10][C:11]=2[O:12][CH2:13][CH:14]2[CH2:16][CH2:15]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:20][C:21]([CH3:29])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[NH2:22]>>[CH3:20][C:21]([NH:22][C:17]([C:9]1[CH:8]=[CH:7][C:6]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5]2)=[C:11]([O:12][CH2:13][CH:14]2[CH2:15][CH2:16]2)[N:10]=1)=[O:19])([C:23]1[N:27]=[C:26]([CH3:28])[O:25][N:24]=1)[CH3:29]

Komponenten

3

Edukt 2

HCID 435592512-(5-Methyl-1,2,4-oxadiazol-3-yl)propan-2-amineHCID 710875595-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid

Produkt 1

HCID 710935755-Cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid [1-methyl-1-(5-methyl-[1,2,4]oxadiazol-3-yl)-ethyl]-amide

Versuchsvorschrift

The title compound was synthesized in analogy to Example 1, using 5-cyclopentyl-6-cyclopropylmethoxy-pyridine-2-carboxylic acid (Example 39 b) and α,α,5-trimethyl-1,2,4-oxadiazole-3-methanamine (CAN 1153831-97-0, Example 33 d) as starting materials, MS (LC/MS): 385.2 [M+H]+.

Quellen und Nachweise

ORD-Eintrag
ord-e6809d8dfac3448d8003dc18331fa139
Quelldatensatz
uspto-grants-2016_04
Patentnummer
US09321727B2

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