Hydrochloric Acid → 2-(1,2,4-Oxadiazol-3-yl)propan-2-amine hydrochloride
Reaktionsgleichung
[O:1]1[CH:5]=[N:4][C:3]([C:6]([NH:9]C(=O)OC(C)(C)C)([CH3:8])[CH3:7])=[N:2]1.[ClH:17]>C(OCC)(=O)C>[ClH:17].[CH3:7][C:6]([NH2:9])([C:3]1[N:4]=[CH:5][O:1][N:2]=1)[CH3:8]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
tert-Butyl 2-(1,2,4-oxadiazol-3-yl)propan-2-ylcarbamate (0.668 g, 2.9 mmol) was dissolved in in ethyl acetate saturated with hydrochloride (10 mL) and stirred at room temperature for 0.5 h. Then it was concentrated to give product (0.45 g, 94%); MS (EI): m/e=128.2 [M+H]+.
Aufarbeitung
- concentrationThen it was concentrated
Quellen und Nachweise
- ORD-Eintrag
- ord-60aba888a71a439d9c8060bbefb7bf3b
- Quelldatensatz
- uspto-grants-2016_04
- Patentnummer
- US09321727B2
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