Reaktionsgleichung
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C:14]([OH:16])=O)=[N:6][C:7]=1[O:8][CH2:9][C:10]([F:13])([F:12])[F:11].[CH3:17][C:18]([CH3:25])([C:20]1[S:21][CH:22]=[CH:23][N:24]=1)[NH2:19]>>[CH3:17][C:18]([NH:19][C:14]([C:5]1[CH:4]=[CH:3][C:2]([Br:1])=[C:7]([O:8][CH2:9][C:10]([F:11])([F:12])[F:13])[N:6]=1)=[O:16])([C:20]1[S:21][CH:22]=[CH:23][N:24]=1)[CH3:25]Komponenten
3
Versuchsvorschrift
The title compound was synthesized in analogy to Example 280c, using 5-bromo-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 282a) and α,α-dimethyl-2-thiazolemethanamine (Example 12c) as starting materials, MS (EI): m/e=424.3 [M+H]+.
Quellen und Nachweise
- ORD-Eintrag
- ord-133d0153ffde4d5d834e3d0b1fceef1c
- Quelldatensatz
- uspto-grants-2016_04
- Patentnummer
- US09321727B2
Verknüpfte Notizen
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