HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
L-Leucinol → 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | L-Leucinol | HCID 111307 | — |
| Edukt | 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid | HCID 71087649 | — |
| Produkt | 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-1-hydroxymethyl-3-methyl-butyl)-amide | HCID 71113275 | — |
Reaktionsschritte
The title compound was synthesized in analogy to Example 280c, using 5-cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 301a) and L-leucinol (CAN 17016-87-4) as starting materials, MS (EI): m/e=361.3 [M+H]+.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09321727B2 |
| Quelldatensatz | uspto-grants-2016_04 |
| ORD ID | ord-32f12e51eca14e1996937fca65265b93 |
| Quellennotiz | uspto-grants-2016_04 |